Fioricet Interactions

The effects of one or more of the drugs in Fioricet may enhance the effects of other drugs. These may include:

  • Monoamine oxidase inhibitors (MAOIs),¬†antidepressants¬†including Marplan (isocarboxazid), Nardil (phenelzine), and others
  • Tranquilizers such as chlordiazepoxide (Librium)
  • Sedative-hypnotics, such as prescription sleeping pills
  • General anesthesia drugs

Remember to always tell your doctor about any prescription, non-prescription, over-the-counter (OTC), illegal and recreational drugs, herbal remedies, nutritional and dietary supplements, and all other drugs and treatments you’re taking.

Fioricet and Alcohol

Ask your doctor about whether to avoid alcohol while taking Fioricet. The drug may enhance the intoxicating effects of alcohol. Drinking while on Fioricet may increase the risk of liver damage from the acetaminophen.

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