Fioricet contains three compounds. Each has a different action to help manage pain: Butalbital: This compound is a type of barbiturate. It reduces anxiety and causes drowsiness by relaxing your muscles and nervous system. As it can be habit-forming, medications with butalbital are tightly regulated. Acetaminophen: This is a widely used medication to reduce pain … Read more
Acetaminophen, butalbital, and caffeine is used to relieve tension headaches. Acetaminophen is in a class of medications called analgesics (pain relievers). It works by changing the way the body senses pain. Butalbital is in a class of medications called barbiturates. It works by having a relaxing effect on the brain and central nervous system (CNS). … Read more
Chlordiazepoxide; Amitriptyline: (Moderate) Additive CNS and/or respiratory depression may occur. Additionally, barbiturates may increase the metabolism of chlordiazepoxide. Chlordiazepoxide is a CYP3A4 substrate. Barbiturates are CYP3A4 inducers. Chlordiazepoxide; Clidinium: (Moderate) Additive CNS and/or respiratory depression may occur. Additionally, barbiturates may increase the metabolism of chlordiazepoxide. Chlordiazepoxide is a CYP3A4 substrate. Barbiturates are CYP3A4 inducers. Chloroprocaine: … Read more
Carbinoxamine: (Moderate) Additive CNS depression may occur if barbiturates are co-used with sedating antihistamines, such as carbinoxamine. Monitor for additive CNS and respiratory effects, and warn about the potential effects to driving and other activities. Cardiac glycosides: (Moderate) Hepatic enzyme inducing drugs, such as barbiturates, can accelerate the metabolism of digoxin, decreasing its serum concentrations. … Read more
Bupropion: (Moderate) Bupropion is associated with a dose-related risk of seizures. Excessive use of psychostimulants, including caffeine, is associated with an increased seizure risk and may increase this risk during the concurrent use of bupropion. Carefully consider a patient’s caffeine intake from all sources, including medicines. Monitor for irritability, tremor, increased blood pressure, insomnia and … Read more
Abacavir; Lamivudine, 3TC; Zidovudine, ZDV: (Minor) Both acetaminophen and zidovudine, ZDV undergo glucuronidation. Competition for the metabolic pathway is thought to have caused a case of acetaminophen-related hepatotoxicity. This interaction may be more clinically significant in patients with depleted glutathione stores, such as patients with acquired immunodeficiency syndrome, poor nutrition, or alcoholism. Abemaciclib: (Major) Avoid … Read more
Why is Acetaminophen, Butalbital, and Caffeine prescribed? Acetaminophen, butalbital, and caffeine is used to relieve tension headaches. Acetaminophen is in a class of medications called analgesics (pain relievers). It works by changing the way the body senses pain. Butalbital is in a class of medications called barbiturates. It works by having a relaxing effect on … Read more
Many people wake up in the morning with a headache. Other people get headaches when their level of tension increases. Migraines, as a more severe form of a headache, can be debilitating. However, it is a tension headache that is actually the most common type of the disorder, affecting somewhere between 30 to 78 percent of … Read more
Fioricet is a prescription drug often used to treat tension headaches that contains the following active ingredients: Acetaminophen 300 mg Butalbital 50 mg Caffeine 40 mg Each of these three ingredients stays in the body for different lengths of time, meaning that Fioricet can stay in the system for up to eight days. Duration of Effects of … Read more
There haven’t been enough strong clinical studies looking at Fioricet and its effects on pregnancy, so it’s not completely known how safe it is during pregnancy. A study found that Fioricet could potentially raise the risk of heart problems in unborn babies. In addition, there has been a report of a newborn experiencing withdrawal seizures … Read more